Oral Histories

Interview of James R. Lupski

Pew Scholar in the Biomedical Sciences: James R. Lupski
Pew Scholars Program in the Biomedical Sciences
Science, Medicine, and Technology
Maestrejuan, Andrea R.
Lupski, James R.
Supporting Documents:
Records relating to the interview are located in the office of the UCLA Library's Center for Oral History Research.
Regents of the University of California, UCLA Library.
Series Statement:
Interviews in this series, sponsored by the Pew Charitable Trusts, document the research of "outstanding scientists from quality institutions" chosen by the Pew Scholars Program to receive four-year stipends.
Contracts Charcot-Marie-Tooth (CMT) disease as a child and decides to become a physician to investigate the genetic component of disease; majors in chemistry at New York University (NYU); studies brain receptors in the David Schuster laboratory; learns gene cloning technology during two semesters at Cold Spring Harbor Laboratory; earns an M.D./Ph.D. at the NYU Postgraduate Medical School; studies the macromolecular synthesis operon in the G. Nigel Godson laboratory; sets the goal of finding the CMT gene; becomes an intern, resident, and later professor at Baylor College of Medicine; examines the incidence and genetics of CMT in a large Cajun family in Louisiana; discovers that CMT is not caused by a mutation in a single gene but by three copies of a normal gene; interest in bacterial genetics; the funding of scientific research; the clinical application of basic science research.