Oral Histories

Interview of Jeffrey T. Holt

Pew Scholar in the Biomedical Sciences: Jeffrey T. Holt
Pew Scholars Program in the Biomedical Sciences
Science, Medicine, and Technology
Hathaway, Neil D.
Holt, Jeffrey T.
Supporting Documents:
Records relating to the interview are located in the office of the UCLA Library's Center for Oral History Research.
Regents of the University of California, UCLA Library.
Series Statement:
Interviews in this series, sponsored by the Pew Charitable Trusts, document the research of "outstanding scientists from quality institutions" chosen by the Pew Scholars Program to receive four-year stipends.
Childhood in Battle Creek, Michigan; attends Interlochen music camp; enters Kalamazoo College; the Vietnam War and the draft; Holt's science role models; college biology in the early 1970s; learns laboratory research as a fellow at the National Heart, Lung, and Blood Institute; the National Institutes of Health physician-scientist training program; attends the University of Michigan School of Medicine; university hospitals and community hospitals; specialization in pathology research; how oncogenes react differently in mice and humans; how the practice of medicine differs from research; brings pathology insights to cancer research; the difficulty of applying molecular biology cancer research in clinical practice; the limits of epidemiological cancer research; Arthur W. Nienhuis; Nienhius's lab management; research on antisense fos; technical constraints on antisense experiments; the future of antisense research; applies for a patent for a topical antisense delivery system; applying fos antisense research to human cancer; Inder M. Verma; the possibility of finding a simple model for cancer; potential applications of topical antisense; marketing basic science research to the public.